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A first-of-its-kind combination of prebiotics and probiotics

Your baby’s gut shapes their entire future. Persephone helps nurture it from day one.

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Science-Backed

Developed by leading microbiome scientists and pediatricians (who are also parents).

Tailored for Babies

Uniquely built to replenish key beneficial microbes missing in nine out of ten babies today.**

Clean and Safe

3rd-party tested. Screened for heavy metal and major allergens. Clean Label Project Certified.

Clinically Validated

For safety and effectiveness in a randomized, double-blind placebo-controlled study*

The only complete
probiotic for today’s
babies

4

Keystone Strains

every baby needs to build a healthy foundation for life

HMO
prebiotic blend

to promote bacterial longevity in the gut

100%

daily recommended value of Vitamin D for infants

Probiotic Blend Made in the USA
Clinically-Studied
Clean Label Project Verified
Every Batch Third-Party Tested & Deep DNA Sequenced
No Artificial Additives
Probiotic Blend Made in the USA
Clinically-Studied
Clean Label Project Verified
Every Batch Third-Party Tested & Deep DNA Sequenced
No Artificial Additives
Probiotic Blend Made in the USA
Clinically-Studied
Clean Label Project Verified
Every Batch Third-Party Tested & Deep DNA Sequenced
No Artificial Additives
Probiotic Blend Made in the USA
Clinically-Studied
Clean Label Project Verified
Every Batch Third-Party Tested & Deep DNA Sequenced
No Artificial Additives

Our My Baby Biome study demonstrated that

9 out of 10

U.S babies are born without the essential levels of critical gut bacteria they need to build a thriving microbiome.

For generations, babies were born with a resilient gut microbiome, rich in protective bacteria that support immunity, digestion, and development.

Our study indicates that’s no longer the norm.

Without these critical bacteria, babies face a higher risk of:

Food sensitivities & eczema Asthma & allergies Weakened immunity Chronic inflammation

Precision science
furthering nature’s
brilliance

At Persephone, we’ve harnessed the power of nature and science to develop a first-of-its kind synbiotic – pairing keystone probiotics with prebiotics found in human breast milk. This precision pairing was born from the largest U.S. study on the infant gut microbiome that our team conducted and is designed to nurture a thriving gut ecosystem during the most critical years of development.

Establishes beneficial bacteria populations

Support digestive health

Promotes healthy immune development

Supports brain development

Stephanie Culler, PhD

CEO & Co-Founder, Microbiome Scientist & Mom

I'm Stephanie, a mom, scientist and founder

I had studied the microbiome for over a decade, but it wasn’t until I became a mom that I realized what was missing in our babies.


Conversations with the leading pediatric experts and the results of our My Baby Biome study revealed a shocking global trend: most babies lack the gut microbes they need for lifelong health.


I was shocked that no one had solved this problem.

So I am. This isn’t just my company, it’s my calling.

Our Story

It is clear that the infant gut microbiome today in industrialized societies is different than in the past with loss of keystone, pioneer microbes. The good news is that this significant deficit is addressable.

Richard Insel, M.D.

Pediatrician and Research Professor