A first-of-its-kind combination of prebiotics and probiotics
Your baby’s gut shapes their entire future. Persephone helps nurture it from day one.
Science-Backed
Developed by leading microbiome scientists and pediatricians (who are also parents).
Tailored for Babies
Uniquely built to replenish key beneficial microbes missing in nine out of ten babies today.**
Clean and Safe
3rd-party tested. Screened for heavy metal and major allergens. Clean Label Project Certified.
Clinically Validated
For safety and effectiveness in a randomized, double-blind placebo-controlled study*
probiotic for today’s
babies

4
Keystone Strains
every baby needs to build a healthy foundation for life
HMO
prebiotic blend
to promote bacterial longevity in the gut
100%
daily recommended value of Vitamin D for infants

Our My Baby Biome study demonstrated that
9 out of 10
U.S babies are born without the essential levels of critical gut bacteria they need to build a thriving microbiome.
For generations, babies were born with a resilient gut microbiome, rich in protective bacteria that support immunity, digestion, and development.
Our study indicates that’s no longer the norm.
Without these critical bacteria, babies face a higher risk of:
furthering nature’s
brilliance
At Persephone, we’ve harnessed the power of nature and science to develop a first-of-its kind synbiotic – pairing keystone probiotics with prebiotics found in human breast milk. This precision pairing was born from the largest U.S. study on the infant gut microbiome that our team conducted and is designed to nurture a thriving gut ecosystem during the most critical years of development.


Establishes beneficial bacteria populations
Support digestive health
Promotes healthy immune development
Supports brain development

Stephanie Culler, PhD
CEO & Co-Founder, Microbiome Scientist & Mom
I had studied the microbiome for over a decade, but it wasn’t until I became a mom that I realized what was missing in our babies.
Conversations with the leading pediatric experts and the results of our My Baby Biome study revealed a shocking global trend: most babies lack the gut microbes they need for lifelong health.
I was shocked that no one had solved this problem.
So I am. This isn’t just my company, it’s my calling.
It is clear that the infant gut microbiome today in industrialized societies is different than in the past with loss of keystone, pioneer microbes. The good news is that this significant deficit is addressable. ![]()
Richard Insel, M.D.
Pediatrician and Research Professor























